Table 1.
Sample collection | ALT (U/L) | anti-HEV IgM | anti-HEV IgG | HEV RNA (Lab II) | HEV RNA (Lab III) | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Lab I | Lab II | Lab III | Lab I | Lab II | Lab III | Serum | Stool | Serum | Stool | ||
Day 0 | 408 | + | − | − | + | − | − | − | − | − | − |
Day 7 | 155 | + | NA | NA | − | NA | NA | NA | NA | − | NA |
Day 14 | 52 | NA | − | − | NA | − | − | − | NA | − | NA |
Day 28 | 57 | − | − | NA | − | − | NA | NA | − | − | − |
Week 7–10 | 44–68 | + | − | − | + | − | − | − | NA | − | NA |
Polymerase chain reaction assay for HEV RNA performed by in-house assays at Centers for Disease Control and Prevention (CDC) and in the authors’ laboratories.
ALT, alanine aminotransferase; IgM, immunoglobulin M; IgG, immunoglobulin G; Lab I, commercial diagnostic laboratory using in-house anti-HEV EIAs; Lab II, CDC hepatitis laboratory – RPC DSI anti-HEV EIAs; Lab III, authors’ laboratory – Wantai anti-HEV EIAs; +, positive; −, negative; NA, not available (test not perfomed); EIAs, enzyme immunoassays.