Table II.
Characteristics of Liposome Formulations
| Group | Hydrodynamic diameter, nm | PDI | Zeta potential mV | EE % | Drug content mg/ml |
|---|---|---|---|---|---|
| A | 140±5 | 0.122±0.03 | −28.7±4 | 57±3 | 15±3 |
| B | 132±6 | 0.120±0.04 | −31.1±1 | 54±6 | 15±4 |
| C | 133±8 | 0.117±0.04 | −30.4±4 | 60±4 | 17±2 |
| D | 125±4 | 0.181±0.03 | −40±4 | 49±2 | 13±1 |
| E | 150±3 | 0.112±0.03 | −34.7±1 | 60±1 | 16±1 |
| F | 148±6 | 0.131±0.04 | −32±2 | 61±1 | 16±1 |
| G | 170±5 | 0.179±0.03 | −32.7±4 | 60±4 | 16±2 |
| H | 131±8 | 0.082±0.08 | −24±4 | 48±6 | 13±2 |
| I | 127±2 | 0.098±0.01 | −9.7±2 | 51±4 | 13±3 |
| J | 123±3 | 0.112±0.01 | 10.3±4 | 52±7 | 14±2 |
All determinations were performed at least in duplicate; values, mean±SEM