TABLE 1.
Rates of Pancreatitis Among Patients With PHPT
| References | Country | All PHPT Patients | PHPT Patients With Pancreatitis, n (%) | Type of Pancreatitis | Patients Diagnosed With PHPT During Pancreatitis Workup, n (%) | PHPT-Pancreatitis Patients With Coexisting Pancreatitis Etiologies, n (%)* | Resolution of Pancreatitis After Parathyroidectomy, n/x (%) |
|---|---|---|---|---|---|---|---|
| Felderbauer et al11 | Germany | 1259 | 57 (4.5) | 16 AP, 15 CP | — | Coexisting etiologies excluded | — |
| Khoo et al12 | USA | 684 | 10 (1.5) | All AP | — | 4 (40) | 0/1 (0) |
| Bhadada et al13 | India | 59 | 9 (15.3) | All CP | — | Coexisting etiologies excluded | 6/6 (100) |
| Jacob et al14 | India | 101 | 13 (12.9) | 6 AP, 6 RP, 1 CP | 12 (92.3) | 5 (38.5) | — |
| Agarwal et al15 | India | 87 | 6 (6.9) | 5 RP, 1 CP | 5 (83.3) | — | 4/5 (80) |
| Carnaille et al16 | France | 1224 | 40 (3.3) | 18 AP, 8 RP, 14 CP | 27 (67.5) | Excluded patients with gallstones | 17/40 (42.5) |
| Shepherd17 | Australia | 137 | 7 (5.1) | All AP | 5 (71.4) | 2 (28.6) | — |
| Koppelberg et al18 | Germany | 234 | 13 (5.6) | 9 AP, 4 CP | 10 (76.9) | 5 (38.5) | 7/10 (70) |
| Sitges-Serra et al19 | Spain | 86 | 7 (8.1) | 3 AP, 1 RP, 3 CP | — | — | — |
| Bess et al20 | USA | 1153 | 17 (1.5) | 10 AP, 7 CP | — | 11 (64.7) | 5/17 (29.4) |
| Total | 5024 | 179 (3.6) | 79 AP, 20 RP, 54 CP | 59 (74.6) | 27 (45) | 39/79 (49.3) |
*
Primarily gallstones or sludge, alcohol ingestion, and triglyceride elevations.
AP indicates acute pancreatitis; CP, chronic pancreatitis; PHPT, primary hyperparathyroidism; RP, recurrent pancreatitis; x, number of patients who underwent surgery with removal of an adenoma.