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. Author manuscript; available in PMC: 2016 May 8.
Published in final edited form as: Circ Res. 2015 May 8;116(10):1700–1711. doi: 10.1161/CIRCRESAHA.116.304377

Figure 2. miRNAs and reprogramming.

Figure 2

miRNAs promote the generation of cardiomyocytes via a number of mechanisms. Fibroblasts can be reprogrammed into cardiomyocytes by miRNAs directly or through an intermediate iPSC state. miRNAs also promote cardiac progenitor cell (CPC) and embryonic stem cell (ESC) cardiac differentiation. miRNAs can promote or inhibit cardiomycyte proliferation.