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Effects of neonatal repeated propofol administration on open field locomotor activity of rats at P28 by (A) distance moved (in time bins), (B) movement duration (in time bins), (C) total distance moved and (D) total movement duration. (E) Time spent in the center area (20×20 cm) was also measured as an initial measure of anxiety behavior. Symbols and bars indicate the mean ± SEM. Control (male, n=8; female, n=13) and Propofol (male, n=10; female, n=16). *p<0.05 vs control female.
