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Inhibition of NMDA-induced ROS production by the selected 7-methoxy-N-(substituted phenyl)benzofuran-2-carboxamide derivatives with substitutions at R1 (A), R2 (B), and R3 (C) positions in primary cortical neuronal culture. Memantine was tested as a reference. The values are expressed as the Mean ± SEM of three individual assays. Statistical analysis of the data was performed by independent samples t-test to determine the significant inhibition. *p<0.05; **p<0.01; ***p<0.001.
