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. Author manuscript; available in PMC: 2016 May 8.
Published in final edited form as: Biochem Biophys Res Commun. 2015 Mar 20;460(3):596–602. doi: 10.1016/j.bbrc.2015.03.075

Figure 2. WSS, but not S1P, stimulated conversion of pro MT1-MMP to the active form in ECs seeded on 3D collagen matrices.

Figure 2

(A) Representative western blots are shown from ECs treated with or without 5.3 dyn/cm2 WSS for 2 or 6hr in the presence or absence of 1μM S1P. Cell extracts were probed with antibodies directed to MT1-MMP (top blot) or GAPDH (bottom blot). Densitometric analyses of band intensities for (B) Pro MT1-MMP and (C) Active MT1-MMP levels normalized to GAPDH.