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. 2015 May 12;10(5):e0126187. doi: 10.1371/journal.pone.0126187

Table 2. Socio-demographic and biological characteristics according to malaria attacks and results of random-effect negative binomial regression models exploring factors associated with clinical malaria cases (n = 3,812).

Characteristics Subcategory Number of persons n = 199 (100%) Number of person-trimester n = 3,812 (100%) Clinical malaria cases Simple regression analysis Multiple regression analysis
No n = 3,572 n (%) Yes n = 240 n (%) IRR (95% CI) P-value aIRR (95% CI) P-value
Mosquitoes collectors No - 2,440 (64) 2,286 (64) 154 (64) 1 1
yes - 1,372 (36) 1,286 (36) 86 (36) 0.97 (0.71–1.33) 0.85 0.89 (0.65–1.22) 0.47
Number of nights of collections 0 - 2,440 (64) 2,286 (64) 154 (64) 1
1 - 461 (12) 430 (12) 31 (13) 0.94 (0.62–1.42) 0.77
2 - 445 (12) 418 (12) 27 (11) 0.94 (0.60–1.48) 0.80
3 and more - 466 (12) 438 (12) 28 (12) 1.05 (0.67–1.66) 0.83
Age group 15–29 years old - 1,615 (42) 1,478 (41) 137 (57) 1 1
30–44 years old - 1,002 (26) 937 (27) 65 (27) 0.59 (0.41–0.87) <0.01 0.59 (0.40–0.88) <0.01
45 years old and over - 1,195 (31) 1,157 (32) 38 (16) 0.27 (0.16–0.45) <0.01 0.31 (0.18–0.53) <0.01
Born at Dielmo No 65 (33) 796 (21) 714 (20) 82 (34) 1 1
Yes 134 (67) 3,016 (79) 2,858 (80) 158 (66) 0.32 (0.19–0.54) <0.01 0.38 (0.24–0.61) <0.01
Biological characteristics
HB type AA 167 (84) 3,330 (87) 3,120 (87) 210 (88) 1
AS 22 (11) 401 (11) 381 (11) 20 (8) 0.82 (0.39–1.76) 0.62
AC 2 (1) 54 (1) 51 (1) 3 (1) 0.50 (0.06–4.15) 0.52
ABO Group O 63 (32) 1,273 (33) 1,187 (33) 86 (36) 1
A 57 (29) 1,316 (35) 1,224 (34) 92 (38) 1.08 (0.61–1.91) 0.80
B 48 (24) 1,028 (27) 978 (27) 50 (21) 0.70 (0.37–1.32) 0.27
AB 9 (5) 131 (3) 126 (4) 5 (2) 0.59 (0.15–2.29) 0.45
Others characteristics
Treatment period Quinimax 104 1,104 (29) 1,031 (29) 73 (30) 1 1
Chloroquine 106 1,006 (26) 913 (26) 93 (39) 1.07 (0.76–1.49) 0.70 1.16 (0.77–1.75) 0.49
AQ+SP/ACT 110 720 (19) 678 (19) 42 (18) 0.58 (0.38–0.88) 0.01 0.74 (0.48–1.16) 0.19
ACT+LLINs 119 982 (26) 950 (27) 32 (13) 0.28 (0.18–0.45) <0.01 0.43 (0.27–0.70) <0.01
Quarter of the year First quarter of the year 166 841 (22) 801 (22) 40 (17) 1 1
Second quarter of the year 169 948 (25) 899 (25) 49 (20) 0.98 (0.66–1.46) 0.92 0.96 (0.65–1.42) 0.84
Third quarter of the year 182 1,040 (27) 963 (27) 77 (32) 1.41 (0.97–2.04) 0.07 1.31 (0.88–1.95) 0.19
Fourth quarter of the year 173 983 (25) 909 (25) 74 (31) 1.53 (1.06–2.20) 0.02 1.47 (1.02–2.13) 0.04
EIR (Entomological Inoculation Rate per person-trimester) - 1.007 (1.004–1.01) <0.01 1.003 (0.999–1.007) 0.10

IRR: Incidence rate ratio; aIRR: adjusted incidence rate ratio.