Table 3.

Association between exposure to oral bisphosphonates and atrial fibrillation

	Cases n = 726 (%)	Controls n = 7260 (%)	Crude OR (95 % CI)	Adjusted OR (95 % CI)
Current	373 (51)	3129 (43)	1.71 (1.41–2.08)	1.78 (1.46–2.16)
Recent	78 (11)	667 (09)	1.68 (1.26–2.23)	1.70 (1.27–2.28)
Past	96 (13)	1006 (14)	1.38 (1.06–1.80)	1.41 (1.07–1.85)
Distant past	179 (25)	2458 (34)	Reference	Reference

Adjusted for angina pectoris, heart failure, antihypertensive drugs, myocardial infarction, use of lipid lowering drugs, oral corticosteroids, and antithyroid drugs. Categories of users: current (0–90 days prior to index date), recent (91–180 days), past (181–365 days), and distant past (365+ days)

CI confidence interval, OR odds ratio