Table 5.
Characteristics of the whole population according to C-peptide concentration tertiles—ANOVA
| Variables | I tertile | II tertile | III tertile | p value |
|---|---|---|---|---|
| C-peptide range (ng/ml) | 0.80–1.36 | 1.40–2.02 | 2.03–3.80 | |
| Age (years) | 54 ± 7 | 53 ± 5 | 52 ± 5 | 0.69 |
| BMI (kg/m2) | 25.7 ± 5 | 22.9 ± 3 | 26.4 ± 5 | 0.02 |
| LBMD T-score | −1.28 ± 1 | −1.10 ± 1 | −0.43 ± 1 |
0.03 0.02a |
| LBMD Z-score | −0.25 ± 1 | −0.14 ± 1 | 0.51 ± 1 | 0.04 |
| FBMD T-score | −1.15 ± 1 | −1.30 ± 1 | −0.95 ± 1 | 0.50 |
| FBMD Z-score | −0.27 ± 0.9 | −0.42 ± 1 | −0.06 ± 1 | 0.43 |
| Calcium (mg/dL) | 9.4 ± 0.3 | 9.4 ± 0.4 | 9.3 ± 0.4 | 0.78 |
| Phosphorus (mg/dL) | 3.6 ± 0.4 | 3.5 ± 0.5 | 3.7 ± 0.3 | 0.35 |
| Glucose (mg/dL) | 88.2 ± 8 | 89.1 ± 9 | 96.3 ± 9 | 0.003 |
| Insulin (μU/mL) | 6.5 ± 3 | 7.1 ± 2 | 11.9 ± 4 | <0.001 |
| C-peptide (ng/mL) | 1.3 ± 0.4 | 1.6 ± 0.3 | 2.5 ± 0.5 | <0.001 |
| HbA1c (%) | 5.6 ± 0.2 | 5.6 ± 0.3 | 5.7 ± 0.3 | 0.69 |
| PTH (pg/mL) | 47.6 ± 18 | 45.8 ± 21 | 42.1 ± 18 | 0.54 |
| 25OH vit D (ng/mL) | 25.1 ± 11 | 25.9 ± 9 | 27.9 ± 11 | 0.59 |
| NTx (nM BCE/nM creatinine) | 25.8 ± 8 | 27.5 ± 6 | 28.9 ± 7 | 0.37 |
| FGF-23 (pg/mL) | 10.6 ± 8 | 8.1 ± 4 | 9.3 ± 5 | 0.35 |
aLBMD: T-score, glucose, and BMI adjusted in the GLM