Table 2. Regression analysis of cognitive outcome.
| Univariate | Multivariate | |||
|---|---|---|---|---|
| Coefficient (95% CI) | p value | Coefficient (95% CI) | p value | |
| Antenatal characteristics | ||||
| SGA 1 | -0.18 (-0.54–0.17) | 0.316 | -0.22(-0.59 0.15) | 0.239 |
| Gestational age | 0.02 (0.01–0.03) | <0.001 | 0.01 (0.01 0.03) | 0.003 |
| Multiple gestation | 0.21 (-0.10–0.52) | 0.187 | -0.03 (-0.35 0.29) | 0.851 |
| Male gender | -0.05 (-0.31–0.21) | 0.716 | --- | --- |
| Neonatal characteristics | ||||
| Asphyxia (pH) | -0.19 (-0.79–0.42) | 0.525 | --- | --- |
| Asphyxia (Apgar) | -0.34 (-0.63–0.05) | 0.022 | -0.08 (-0.39 0.22) | 0.603 |
| Necrotizing Enterocolitis | -0.31(-0.97 0.34) | 0.349 | --- | --- |
| Sepsis | - 0.5 (-0.88–0.13) | 0.008 | -0.29 (- 0.68 0.09) | 0.140 |
| BPD 2 | - 0.35 (-0.63–0.07) | 0.015 | -0.08 (- 0.41 0.24) | 0.606 |
| Major brain lesions | -1.02 (-1.41–0.64) | <0.001 | - 0.91(-1.33–0.49) | <0.001 |
| Characteristics related to the mother | ||||
| Socio-economic status (ref: high) | ||||
| Middle | - 0.61 (-0.91–3.17) | <0.001 | -0.53 (- 0.85–0.22) | 0.001 |
| Low | - 0.98 (-1.35–0.61) | <0.001 | - 0.99 (-1.39–0.59) | <0.001 |
| Smoking | - 0.23 (-0.57 0.10) | 0.169 | -0.10 (- 0.43 0.22) | 0.532 |
1: SGA: Small for gestational age.
2: BPD: bronchopulmonary dysplasia.
Values are coefficients (95% confidence interval) calculated with linear regression. The variables with p< 0.2, were retained for the multivariate regression, except for SGA, retained in all the analysis.