Table 2.

Mean value, standard deviation and median value (in brackets) of the diffusion metrics in cortical and subcortical gray matter from MS patients and controls

		Controls	Patients	p value
cGM	MK	0.73 ± 0.06 (0.73)	0.68 ± 0.01 (0.68)	<0.001
	FA	0.13 ± 0.05 (0.13)	0.16 ± 0.04 (0.16)	<0.001
	MD	1.13 ± 0.13 (1.12)	1.19 ± 0.17 (1.2)	0.15
	AD	1.22 ± 0.15 (1.23)	1.36 ± 0.07 (1.36)	<0.001
	RD	1.01 ± 0.08 (1.06)	1.12 ± 0.09 (1.1)	<0.001
sGM	MK	0.74 ± 0.01 (0.74)	0.71 ± 0.01 (0.72)	0.009
	FA	0.12 ± 0.05 (0.12)	0.17 ± 0.03 (0.18)	<0.001
	MD	1.11 ±0.08 (1.11)	1.18 ±0.17 (1.16)	0.06
	AD	1.24 ± 0.11 (1.23)	1.34 ± 0.08 (1.34)	0.005
	RD	1.02 ± 0.03 (1.0)	1.11 ± 0.01 (1.11)	0.002

Note: All parameters other than MD (10⁻³ mm²/sec) are dimensionless.

Abbreviations: cGM = cortical gray matter, sGM = subcortical gray matter, MK = mean kurtosis; FA = fractional anisotropy, MD = mean diffusivity; AD = axial diffusivity, RD = radial diffusivity