Fig 1. A—DST nano-T temperature logging device, as supplied; B—illustration of vaginal ring device with cavity for insertion of temperature logger.

C—construction of temperature logging device encapsulated in silicone elastomer tubing for vaginal testing in macaques; C1 shows the silicone elastomer tubing (8.0 mm overall diameter); C2 shows the logger inserted into the silicone elastomer tubing; C3 shows the tubing end-sealed with silicone elastomer.