Fig 2. In vitro testing of DST nano-T temperature logging devices using sampling rates of 8 and 60 min.

Devices were placed in a shaking orbital incubator set to 37°C, removed from the incubator at 120 min, returned to the incubator at 240 min, and then finally removed at 360 min. A—devices as supplied, i.e. non-encapsulated. B—devices sealed in silicone elastomer tubing. C—devices sealed in silicone elastomer tubing and placed in 10 mL of simulated vaginal fluid contained in a glass beaker.