Table A1.
Characteristic | Dropped Out (n = 52) |
Completed (n = 146) |
P | ||
---|---|---|---|---|---|
No. | % | No. | % | ||
Age, years | |||||
Median | 55 | 55 | |||
Range | 19 to 83 | 20 to 84 | |||
≥ 50 | 32 | 62 | 87 | 60 | |
Months since diagnosis | |||||
Median | 34.8 | 39.7 | |||
Range | 8.8 to 228.0 | 7.3 to 423.2 | |||
≥ 36 | 26 | 50 | 80 | 55 | |
BMI, kg/m2 | |||||
Median | 28.5 | 27.1 | |||
Range | 17.7 to 38.9 | 17.3 to 49.4 | |||
< 25 (underweight to normal) | 14 | 27 | 50 | 34 | |
25 to 30 (overweight) | 19 | 37 | 48 | 33 | |
≥ 30 (obese) | 19 | 37 | 48 | 33 | |
Strata | |||||
WBI, WFU | 4 | 8 | 16 | 11 | |
WBI, CCOP | 20 | 38 | 40 | 27 | |
PBI, WFU | 14 | 27 | 46 | 32 | |
PBI, CCOP | 14 | 27 | 44 | 30 | |
ECOG performance status | |||||
0 | 22 | 42 | 72 | 49 | |
1 | 25 | 48 | 69 | 47 | |
2 | 5 | 10 | 5 | 3 | |
Sex | |||||
Female | 33 | 63 | 73 | 50 | |
Male | 19 | 37 | 73 | 50 | |
Race | |||||
Hispanic | 0 | 0 | 1 | 1 | |
Asian | 1 | 2 | 0 | 0 | |
Black | 5 | 10 | 11 | 8 | |
White | 46 | 88 | 90 | 91 | |
Marital status* | |||||
Single | 9 | 18 | 13 | 9 | |
Married or married-like | 34 | 67 | 105 | 72 | |
Separated, divorced, or widowed | 8 | 16 | 28 | 19 | |
Education* | .006 | ||||
≤ High school | 24 | 48 | 38 | 26 | |
Vocational or some college | 19 | 38 | 60 | 41 | |
≥ College graduate | 7 | 14 | 47 | 32 | |
Income, US$* | .019 | ||||
< 20,000 | 23 | 51 | 42 | 34 | |
20,000 to 50,000 | 17 | 38 | 41 | 34 | |
≥ 50,000 | 5 | 11 | 39 | 32 | |
Work outside home* | 14 | 27 | 45 | 31 | |
Diagnosis | |||||
Primary brain tumor | 31 | 60 | 99 | 68 | |
Brain metastasis | 15 | 29 | 38 | 26 | |
PCI | 6 | 12 | 9 | 6 | |
Primary tumor type | n = 31 | n = 99 | |||
Glioblastoma multiforme | 4 | 13 | 19 | 19 | |
Anaplastic astrocytoma | 3 | 10 | 11 | 11 | |
Anaplastic oligodendroglioma | 6 | 19 | 10 | 10 | |
Anaplastic oligoastrocytoma | 1 | 3 | 2 | 2 | |
Anaplastic ependymoma | 2 | 6 | 2 | 2 | |
Anaplastic mixed glioma | 0 | 0 | 1 | 1 | |
Low-grade astrocytoma | 1 | 3 | 5 | 5 | |
Low-grade oligodendroglioma | 0 | 0 | 13 | 13 | |
Low-grade oligoastrocytoma | 0 | 0 | 1 | 1 | |
Meningioma | 7 | 23 | 15 | 15 | |
Pilocycstic astrocytoma | 2 | 6 | 4 | 4 | |
Other | 5 | 16 | 16 | 16 | |
Metastasis site | n = 21 | n = 47 | |||
Lung | 11 | 52 | 29 | 62 | |
Breast | 8 | 38 | 8 | 17 | |
Other or unknown | 2 | 10 | 10 | 21 | |
Brain volume, cm3* | |||||
Median | 1,086 | 1,144 | |||
Range | 865 to 1,382 | 901 to 1,624 | |||
≥ 1,200 | 8 | 16 | 44 | 31 | |
CSF volume, cm3* | |||||
Median | 213 | 206 | |||
Range | 122 to 315 | 101 to 376 | |||
≥ 200 | 27 | 53 | 75 | 53 | |
Brain or intracranial volume, %* | .012 (continuous); .035 (dichotomous) | ||||
Median | 83.4 | 84.5 | |||
Range | 78.1 to 89.5 | 74.8 to 92.0 | |||
Lesion or resection volume, cm3* | |||||
0 | 7 | 14 | 16 | 11 | |
< 15 | 36 | 71 | 87 | 61 | |
≥ 15 | 8 | 16 | 40 | 28 | |
Hippocampus involvement* | 10 | 19 | 13 | 9 | .048 |
Location* | |||||
Frontal | 16 | 36 | 46 | 35 | |
Parietal | 4 | 9 | 24 | 18 | |
Occipital | 5 | 11 | 6 | 5 | |
Temporal | 6 | 13 | 27 | 21 | |
Basal ganglia | 4 | 9 | 11 | 8 | |
Cerebellum | 7 | 16 | 10 | 8 | |
Brainstem or spinal cord | 3 | 7 | 6 | 5 |
Abbreviations: BMI, body mass index; CCOP, community clinical oncology program; ECOG, Eastern Cooperative Oncology Group; PBI, partial-brain irradiation; PCI, prophylactic cranial irradiation; WBI, whole-brain irradiation; WFU, Wake Forest University.
Some missing data.