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. 2015 May 12;9:116. doi: 10.3389/fnbeh.2015.00116

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Copyright © 2015 Tuma, Kolinko, Vozeh and Cendelin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Open field test: (A) Superposition of trajectories (frequency of animal presence) for females and males in the arena; (B) Total distance moved (cm); (C) Percentage of time spent with locomotion activity (%); (D) Percentage of thigmotaxis (% moved distance in the 3 cm border zone) and (E) Mean walking speed (cm/s) during locomotion activity periods. Statistical significance was evaluated using a permutational t-test. Within-strain comparison: ^*p < 0.05, ^**p < 0.01, and ^***p < 0.001. Between-strain comparison: ^# p < 0.05, ^## p < 0.01, and ^### p < 0.001. Data are presented as mean ± SEM.