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. 2015 Mar 6;29(5):656–661. doi: 10.1038/eye.2015.18

Table 3. Outlines the treatments, grade of surgeons and outcomes of all patients.

  Patient Indication for choosing BoNTA over surgery Number of injections Dose (frequency) Grade of surgeon Subjective improvement Percentage of improvement Complications
Punctal occlusion 1 Dry eye 3 1.25, 2.5(2) All by fellows A little better All 30% None
    Dry eye 3 1.25, 2.5(2) All by fellows A little better All 30% None
  2 Sjögren's syndrome 1 2.5 Fellow Completely better 100% Very dry eye
  3 Dry eye 6 2.5 All by fellows Completely better 90%,90%,95%, 95%, 90%, 95% Haematoma after last injection
  4 Dry eye 4 5, 2.5(3) All by consultant A lot better but not completely All about 60% Diplopia after last injection
    Dry eye 4 5, 2.5(3) All by consultant A lot better but not completely All about 60%
Canalicular or common canalicular stenosis 5 Medial canthal SCC 3 2.5 All by fellows A lot better but not completely 90%, 80%, 80% None
  6 Rejected Jones tube 2 2.5 All by fellows No better No better None
  7 Unwell with Leukaemia 3 5 First by consultant, all the rest by fellows A lot better but not completely 90%,90%,90% none
  8 Rejected Jones tube 7 2.5 All by fellows A lot better but not completely First 50%, all rest 80–90% None
    Rejected Jones tube 7 2.5 All by fellows A lot better but not completely First 50%, all rest 80–90% None
  9 Rejected surgery due to back problems 10 7.5, 2.5, 5(2), 2.5(6) Three by consultant, seven by fellows A lot better but not completely First 6 treatment 80%, the rest not available None
  10 Disturbed nasal anatomy 3 2.5 All by fellows A lot better but not completely First 50% and the rest 80% None
  11 Medial canthal BCC 2 2.5 All by fellows A little better <50% None
  12 Previously failed DCR, rejected Jones tube 2 2.5 All by consultant A lot better but not completely Both 75% None
    Previously failed DCR, rejected Jones tube 2 2.5 All by consultant A lot better but not completely Both 75% None
  13 Conjunctival SCC 2 2.5 All by fellows A lot better but not completely Both 80% None
  14 Conjunctival SCC 1 2.5 Consultant A lot better but not completely 60% None
NLD stenosis 15 Melanoma of nose and sinus 5 2.5 All by fellows Completely better All 90–98% None
  16 Old age 1 2.5 Consultant A little better 30% None
    Old age 1 2.5 Consultant A little better 30% None
  17 Rejected DCR 1 2.5 Fellow Worse Worse Epiphora got worse

Abbreviations: BoNTA, botulinum toxin A; DCR, dacryocystorhinstomy; NLD, Nasolacrimal duct; SCC, squamous cell carcinoma.