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. 2015 Mar 13;29(5):681–690. doi: 10.1038/eye.2015.24

Figure 1.

Figure 1

Transplantation and bimodal (OCT–fcSLO) in vivo imaging of subretinal PPC-grafts. (a) Overview of PPC transplantation via bolus injection into the subretinal space of retinal dystrophic rats. (b) Bimodal imaging was performed at each time point: day 0 (d0), day 8 (d8), and day 15 (d15); Qtracker (QT) PPC-graft label appears white on fcSLO images. OCT showing subretinal bleb formation and graft (arrowheads); note subretinal bleb contains host cells at d15. Vitreal aggregates atop graft site, an indicator of host-site inflammation (asterisks; also see Supplementary Video S1 of d15 recipient: 1). Results are representative images (n=4, recipients: 1, 2, 7, and 11). Un-injected contralateral eyes served as a negative ‘No transplant' control (dashed box). (c) Representative images of variable graft architecture (aggregation, dispersion, and thickness) at the time of transplantation (d0) (n=4, recipients: 2, 3, 7, and 11). (b, c) Scale bars are 250 μm.