Table 1. Bimodal in vivo imaging findings for PPC transplant recipients.
| Recipient designation (1–15, grouped by injection site outcome) |
OCT findings |
fcSLO findings |
Injection site (noted complications) | ||||
|---|---|---|---|---|---|---|---|
| Day | Day | ||||||
| 0 | 8 | 15 | 0 | 8 | 15 | ||
| 1 | SB | SB, VA | SB, VA | + | + | + | Subretinal |
| 2 | SB | SB, VA | SB, VA | + | + | + | Subretinal |
| 7 | SB | SB, VA | SB, VA | + | + | + | Subretinal |
| 11 | SB | SB, VA | SB, VA | + | + | − | Subretinal |
| 10 | SB | SB | SB | + | − | − | Subretinal (GR) |
| 3 | SB | SB | + | + | Subretinal | ||
| 8 | SB | SB | a | + | a | a | Subretinal (Cat.) |
| 4 | NAD | NAD | + | − | Choroidal | ||
| 5 | NAD | VA | + | − | Choroidal | ||
| 6 | NAD | a | + | a | Choroidal (Cat.) | ||
| 9 | NAD | NAD | NAD | + | − | − | Choroidal |
| 12 | VC | VC | VC | + | + | + | Vitreal (NRP) |
| 13 | VC | VC | VC | + | + | − | Vitreal (NRP) |
| 14 | VC | VC | VC | + | + | − | Vitreal (NRP) |
| 15 | VC | NAD | VA | + | − | − | Vitreal (NRP) |
Abbreviations: Cat., cataract; GR, graft reflux; NAD, nothing abnormal detected. Ophthalmoscopy observations were in concordance with OCT findings above. Ophthalmoscopy could only detect subretinal blebs (SBs) at day 0 and vitreal clouding (VC, graft in the vitreous resulting from neural retinal puncture, NRP), while microscopic vitreal aggregates (VAs, indicators of host-site inflammation) overlying the graft site could not be detected. NAD, Cat., and GR were observed during injection. Presence (+) or absence (−) of fluorescent graft label (Qtracker) across the fundus; heterogeneous signal distribution and redistribution was seen for all recipients with positive signal over time. Blank boxes indicate end point at previous time point.
Cataract formation precluded complete bimodal imaging; OCT was able to resolve the retina and choroid at early stages of cataract formation; however, fcSLO could not penetrate the cataract.