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. Author manuscript; available in PMC: 2015 May 13.
Published in final edited form as: Int J Toxicol. 2014 Jan-Feb;33(1):21–28. doi: 10.1177/1091581813518355

Figure 2.

Figure 2

Whole-body plethysomography in DEP-exposed and challenged Otsuka Long Evans Tokushima fatty (OLETF) obese rats and Long Evans Tokushima-Otsuka (LETO) non-obese rats. Metacholine challenge was performed 24 h after DEP inhalation. Rats were placed in a plethysmograph and treated with saline followed by increasing doses of methacholine (0–100 mg/ml) for 3 min. Enhanced pause (Penh) was obtained for 3 min after each nebulization. *P < 0.05 LETF and OLETF following DEP was significantly greater than those following saline. †P < 0.05 OLETF following DEP was significantly greater than LETO following DEP. Data are means (n = 6 rats/group).