. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: J Antibiot (Tokyo). 2014 Oct 15;68(4):259–266. doi: 10.1038/ja.2014.142

Table 1.

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of thiazole compounds 1 and 2, teicoplanin, and vancomycin against methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-intermediate Staphylococcus aureus (VISA), and vancomycin-resistant Staphylococcus aureus (VRSA) strains.

		MIC and MBC (µgml⁻¹) of thiazole compounds, teicoplanin, and vancomycin against S. aureus

	Strain	1		2		Teicoplanin		Vancomycin

		MIC	MBC	MIC	MBC	MIC	MBC	MIC	MBC
MRSA	NRS107	1.38	2.77	1.40	1.40	0.94	0.94	0.74	1.49
	NRS119	1.38	1.38	1.40	1.40	0.94	0.94	0.74	1.49
	NRS123 (USA400)	1.38	11.07	1.40	5.58	0.94	15.04	0.37	0.37
	NRS194	1.38	5.54	1.40	11.17	0.94	15.04	0.74	0.74
	NRS384 (USA300)	1.38	1.38	1.40	2.80	0.94	15.04	0.74	0.74
	NRS385 (USA500)	1.38	1.38	1.40	1.40	0.94	3.76	0.74	0.74
	ATCC 43300	1.38	2.77	1.40	2.80	0.94	3.76	0.74	0.74

VISA	NRS1	1.38	1.38	0.70	1.40	3.76	7.52	2.97	2.97
	NRS19	1.38	1.38	1.40	1.40	0.94	0.94	2.97	2.97
	NRS37	1.38	1.38	0.70	1.40	7.52	7.52	2.97	2.97

VRSA	VRS1	2.77	2.77	1.40	1.40	120.30	240.60	760.68	760.68
	VRS4	2.77	2.77	0.70	2.80	60.15	60.15	760.68	760.68
	VRS5	2.77	5.54	1.40	5.58	60.15	60.15	760.68	760.68

S. epidermidis	ATCC 35984	2.77	N.D.	0.70	N.D.	N.D.	N.D.	0.74	N.D.

Abbreviation: N.D. = Not Determined