Ref (type)	Population	Outcome, Interventions	Results and statistical analysis	Effect size	Favours
Depression
RCT	117 people; results are reported for the 92 people who completed the follow-up period In review	Hamilton Depression Rating Scale score 6 weeks 11 with nortriptyline (titrated to maintain therapeutic blood levels for depression) 14 with placebo	P = 0.0001	Effect size not calculated	nortriptyline
RCT	117 people; results are reported for the 92 people who completed the follow-up period In review	Proportion of people reporting global satisfaction (measured by asking "Has the medication helped you in any way?") 6 weeks 33/49 (67%) with nortriptyline (titrated to maintain therapeutic blood levels for depression) 17/43 (40%) with placebo	P <0.01	Effect size not calculated	nortriptyline