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. 2015 Jan 13;4(1):9. doi: 10.1186/2193-1801-4-9

Table 1.

Patient and tumour characteristics of randomised patients

GROUPS A + C (n = 57) STATISTICAL SIGNIFICANCE* GROUPS B + D (n = 55)
χ 2 p-value
Age in years, mean (range) 53.9 (33 – 69) - - 53.0 (35 – 69)
Menopausal status, n (%)
PRE-PERI 24 (42.1) 0.572 0.449 29 (52.7)
POST 33 (57.9) 26 (47.3)
TNM Classification, n (%)
T0-T1 2 (3.5) 1 (1.8)
T2 43 (75.4) 46 (83.6)
T3 5 (8.8) 4.881 0.300 5 (9.1)
T4 7 (12.3) 3 (5.5)
N0 32 (56.1) 29 (52.7)
N1-2 25 (43.9) 26 (47.3)
Tumour size in cm (caliper), mean (range) 4.3 (2 – 14) - - 4.2 (1.9 – 14)
Pre NAC nodal involvement, confirmed by biopsy, n (%) 22 (39.3) - - 23 (42.6)
Tumour type, n (%)
Ductal invasive 49 (86.0) 0.410 0.815 47 (85.5)
Lobular invasive (and others) 8 (14.0) 8 (14.5)
Tumour grade, n (%)
Grades 1 and 2 38 (66.7) 2.495 0.287 28 (51.0)
Grade 3 19 (33.3) 27 (49.0)
ER status, n (%)a
Positive (Allred >3) 45 (78.9) 1.732 0.421 37 (67.3)
Negative (Allred < 3) 12 (21.1) 12 (32.7)
HER2 status, n (%)b
Positive (FISH) 11 (19.3) 0.212 0.450 14 (25.9)
Negative 46 (80.7) 41 (74.1)

aER : Oestrogen receptor. bHER2: Human epidermal growth factor receptor 2. Allred : Scoring system for measuring expression of oestrogen receptors in tissue sections. FISH : Fluorescence in-situ hybridisation.

*Various patient and tumour characteristics were not significantly different between Groups (A + C) and (B + D) (p>0.05, Pearson Chi-Square Test).