Table 4.
Disease | Gene symbol | rawP | adjP |
---|---|---|---|
Congenital Abnormalities | GDAP1, GLI3, ALX4, ADAMTS10, TBX1, BBS5, CYP4F22, COL5A1, SOX3, PAX2, NR5A1, KCNJ15, KAL1, MAFB, HOXD13, DDB1, ZIC1 | 9.12E-09 | 6.38E-08 |
Mental Disorders | SYNGAP1, GABRP, PER1, SNCB, VGF, GRIN1, ABCA2, GRIN2D, CPLX1, NALCN, DLGAP3, NEUROD2, NRGN, NEUROG1, SLITRK1 | 6.5E-08 | 2.27E-07 |
Schizophrenia | GABRP, TBX1, GRIN1, NRG2, GRIN2D, CPLX1, NALCN, NRGN, MBNL2, SPTBN4, NEUROG1 | 1.02E-06 | 2.38E-06 |
Syndrome | GLI3, ALX4, WIPF3, ADAMTS10, TBX1, BBS5, SLC29A3, COL5A1, PAX2, KAL1, MEN1, SLITRK1 | 5.60E-05 | 9.80E-05 |
Nelson syndrome | CDK5R2, C2orf16, WIPF3, BBS5, ABCF2, TMEM163, OTX1, BZW2, ZMIZ2, CTNNA2, REPIN1 | 3.00E-04 | 4.00E-04 |
Nervous System Diseases | GDAP1, DTNA, SNCB, SOX3, LRRK2, ABCA2, ARC, SLITRK1, ATP1A3, ZIC1 | 1.50E-03 | 1.80E-03 |
Human immunodeficiency virus | EIF4G1, IL8, PIK3R2, GRIN1, B3GALT2, MAN1C1, GRIN2D, DDB1, KPNB1, TUBA4A | 2.70E-03 | 2.70E-03 |
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment (Benjamini and Hochberg test)