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. 2015 Mar 8;32(5):827–837. doi: 10.1007/s10815-015-0429-y

Table 4.

Diseases association with target genes of mir-1973 and mir-3196

Disease Gene symbol rawP adjP
Congenital Abnormalities GDAP1, GLI3, ALX4, ADAMTS10, TBX1, BBS5, CYP4F22, COL5A1, SOX3, PAX2, NR5A1, KCNJ15, KAL1, MAFB, HOXD13, DDB1, ZIC1 9.12E-09 6.38E-08
Mental Disorders SYNGAP1, GABRP, PER1, SNCB, VGF, GRIN1, ABCA2, GRIN2D, CPLX1, NALCN, DLGAP3, NEUROD2, NRGN, NEUROG1, SLITRK1 6.5E-08 2.27E-07
Schizophrenia GABRP, TBX1, GRIN1, NRG2, GRIN2D, CPLX1, NALCN, NRGN, MBNL2, SPTBN4, NEUROG1 1.02E-06 2.38E-06
Syndrome GLI3, ALX4, WIPF3, ADAMTS10, TBX1, BBS5, SLC29A3, COL5A1, PAX2, KAL1, MEN1, SLITRK1 5.60E-05 9.80E-05
Nelson syndrome CDK5R2, C2orf16, WIPF3, BBS5, ABCF2, TMEM163, OTX1, BZW2, ZMIZ2, CTNNA2, REPIN1 3.00E-04 4.00E-04
Nervous System Diseases GDAP1, DTNA, SNCB, SOX3, LRRK2, ABCA2, ARC, SLITRK1, ATP1A3, ZIC1 1.50E-03 1.80E-03
Human immunodeficiency virus EIF4G1, IL8, PIK3R2, GRIN1, B3GALT2, MAN1C1, GRIN2D, DDB1, KPNB1, TUBA4A 2.70E-03 2.70E-03

rawP: p value from hypergeometric test

adjP: p value adjusted by the multiple test adjustment (Benjamini and Hochberg test)