Table 4.
ORs and 95 % CI for PE and the MTHFR A1298C polymorphism under different genetic models
| genetice model | population | pooled OR [95 % CI] p | Heterogeneity p-value |
Publication Bias | |
|---|---|---|---|---|---|
|
p-value Begg |
p-value Egger |
||||
| Additive (C vs. A) |
Caucasian | 1.074[0.642–1.798]0.785 | 0.004 | 0.497 | 0.374 |
| Asian | 0.988[0.795–1.229]0.917 | 0.399 | 0.317 | – | |
| Overall | 1.067[0.795–1.431]0.667 | 0.009 | 0.748 | 0.256 | |
| Dominant (C-carriers vs.AA) |
Caucasian | 0.821[0.417–1.619]0.57 | 0.004 | 0.042 | 0.037 |
| Asian | 1.023[0.788–1.327]0.865 | 0.5 | 0.317 | – | |
| Overall | 0.965[0.679–1.371]0.844 | 0.02 | 0.108 | 0 | |
| Recessive (CC vs. A-carriers) |
Caucasian | 3.755[0.748–18.852]0.108 | 0.001 | 0.174 | 0.068 |
| Asian | 0.759[0.335–1.717]0.507 | 0.217 | 0.317 | – | |
| Overall | 1.729[0.662–4.52]0.264 | 0.001 | 0.335 | 0 | |