Table 2.
Inter-day assay precision and accuracy for LUME and 97–63 in rat plasma
| LUME (ng/mL) | 97-63 (ng/mL) | |||||||
|---|---|---|---|---|---|---|---|---|
| 3.9 | 10 | 100 | 400 | 3.9 | 10 | 100 | 400 | |
| Meana | 3.8 | 9.7 | 98.1 | 399.9 | 4.0 | 10.2 | 103.7 | 402.3 |
| SD | 0.23 | 0.46 | 5.37 | 18.94 | 0.23 | 0.48 | 4.11 | 16.45 |
| Precision (%)b | 5.90 | 4.72 | 5.48 | 4.74 | 5.77 | 4.75 | 3.97 | 4.09 |
| Accuracy (%)c | 98.11 | 96.87 | 99.42 | 99.99 | 102.55 | 108.38 | 103.72 | 100.58 |
a n = 18; three days with six replicates per day.
b Expressed as % RSD = (SD/mean) × 100.
c Calculated as (mean determined concentration/nominal concentration) × 100.