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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: Biomaterials. 2015 Apr 28;57:142–152. doi: 10.1016/j.biomaterials.2015.04.015

Fig. 7. Histological analysis of hepatic tissue locating embolic material.

Fig. 7

Rows A) and B) provide histological comparison of control and test animal hepatic tissues showing evidence of SELP filling the hepatic arteriole. Both hematoxylin and eosin (H&E) stain and an immunohistochemistry (IHC) stain specific for SELP were used for visualization. The arrow indicates arterioles and the arrowheads indicate the portal venules, for reference. The presence of vacuolization in the hepatocytes of the test animal (encircled) provides more evidence of hypoxic damage induced by occlusion of the hepatic arterial vessels upstream. Images taken at 152X total magnification. Rows C–E) show evidence of SELP within hepatic arterial supply (indicated by the arrows) and no evidence of flow through into the venous drainage via the hepatic central veins (indicated by the arrowheads). Row C, images taken at 30X total magnification, showing a portal triad and its draining central vein. Rows D and E show the portal triad and central vein individually at 152X total magnification. SELP is evident in row D within the arteriole indicated by the arrow. SELP is not evident tracking to or entering the draining central vein in row E.