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. 2015 May 13;5:10181. doi: 10.1038/srep10181

Figure 3. Iron overload damaged the clonogenic capacity of HSPCs. (a–d).

Figure 3

Colony- forming cell (CFC) assays (CFU-E, BFU-E, CFU-GM and CFU-mix) were performed to determine the colony-forming viability of the HPCs. (e)Single cell colony-forming counts of the sorted HSCs were performed to determine the clonogenic capacity of the HSCs. The data are expressed as the means ± SE of three independent experiments. N = 6. ***P < 0.001 vs. CTL; #P < 0.05, ##P < 0.01, ###P < 0.001. vs. IO.