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. 2015 May 13;6:74. doi: 10.3389/fendo.2015.00074

Figure 2.

Figure 2

NT157 inhibits migration ability of OS cell lines. (A) Cell migration of MG-63 and U-2OS cells after treatment with NT157 for 18 h. Columns show the mean of three independent experiments: bars indicate the SE. *p < 0.05, Student’s t-test. (B) Wound-healing assay in MG-63 and U-2OS cells. Representative pictures were taken after 24 h of treatment with NT157 (1–3 μM). Magnification 100×. (C) Inhibition of cell motility is mediated by downregulation of IRS-2 and IRS-1 in MG-63 and U-2OS cells after 24 h of treatment with NT157 (1–3 μM). β-actin was used as loading control.