Table 1.
Patient demographic data.
| Controls | RTLE | LTLE | |
|---|---|---|---|
| N | 12 | 14 | 12 |
| Age, y (SD) | 29.4 (5.0) | 36.2 (11.6) | 35.9 (10.9) |
| Education, y (SD) | 17.9 (4.3) | 13.9 (3.8) | 14.8 (2.8) |
| Sex, M/F | 8/4 | 7/7 | 4/8 |
| Handedness, R/L | 11/1 | 12/2 | 11/1 |
| Language dominance, R/L/BI | 0/12/0 | 1/12/1 | 0/11/1 |
| Disease duration, y (SD) | – | 16.2 (14.2) | 17.0 (11.8) |
| Onset of seizures, y (SD) | – | 20.9 (13.5) | 19.0 (16.0) |
| Presence of MTS, Yes/No | – | 8/6 | 8/4 |
| Other lesions | – | 3 | 2 |
| Verbal memory factor | – | 0.11 (0.99) | −0.20 (1.3) |
| Visual memory factor | – | −0.24 (1.1) | 0.59 (0.93) |
| IQ factor | – | 0.11 (1.0) | 0.38 (1.0) |
RTLE, right temporal lobe epilepsy; LTLE, left temporal lobe epilepsy; y, years; SD, standard deviation; M, male; F, female; R, right; L, left; BI, bilateral; IQ, intelligence quotient.
Characterization of MTS and other lesions was based on radiology (3 T MRI protocol). Three patients with RTLE showed right MTL cortical dysplasia, one with dual pathology of MTS. With respect to extra-MTL lesions, MRI demonstrated cortical dysplasia in the left posterior insula surrounding Heschl’s gyrus in one LTLE patient (with concomitant MTS) and a heterotopion in the left occipital horn in another LTLE patient. All patients were subsequently referred for standard anterior temporal lobe resections.