Figure 1.

Standard viral kinetic model. Target cells (T) are produced at rate s, die with death rate d, and become infected cells (I) with infection rate β by free virus (V). Infected hepatocytes die with rate constant δ. V are released from infected cells at a rate of p and are cleared with a rate c. Treatment is assumed to act by blocking new infection with an effectiveness η, or by blocking virion production with an effectiveness ε.