Table 2. Postprandial serum glucose, insulin and lipid responses to the standard oral glucose (Glu) and white bread (Brd) challenges‡ (Mean values and standard deviations, n 20).
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0 | 15 | 30 | 45 | 60 | 90 | 120 | 150 | 180 | 210 | 240 | 270 | 300 | P§ (treatment×time) | ||||||||||||||||||
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Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | Mean | SD | ||||||
Glucose (mmol/l) | |||||||||||||||||||||||||||||||
Glu | 4.80 | 0.41 | 6.13* | 0.75 | 7.54* | 0.82 | 7.78* | 1.24 | 7.24* | 1.53 | 5.72 | 1.43 | 4.81 | 1.27 | 4.20* | 0.81 | 4.11* | 0.51 | 4.17* | 0.44 | 4.33 | 0.37 | 4.49 | 0.33 | 4.63 | 0.31 | 0.0001 | ||||
Brd | 4.78 | 0.34 | 4.81 | 0.37 | 5.91 | 0.92 | 6.47 | 0.84 | 6.26 | 0.90 | 5.48 | 0.84 | 5.05 | 0.93 | 4.85 | 0.89 | 4.79 | 0.72 | 4.72 | 0.51 | 4.55 | 0.34 | 4.51 | 0.34 | 4.58 | 0.32 | |||||
Insulin (pmol/l) | |||||||||||||||||||||||||||||||
Glu | 9 | 4 | 30* | 13 | 52* | 27 | 54 | 32 | 48 | 27 | 28 | 16 | 16 | 11 | 10† | 4 | 8† | 3 | 7 | 2 | 7 | 2 | 7 | 2 | 7 | 3 | 0.0001 | ||||
Brd | 9 | 3 | 10 | 4 | 30 | 19 | 42 | 20 | 45 | 23 | 32 | 17 | 20 | 7 | 13 | 6 | 11 | 4 | 9 | 3 | 8 | 3 | 7 | 2 | 7 | 2 | |||||
TC (mmol/l) | |||||||||||||||||||||||||||||||
Glu | 4.59 | 0.71 | 4.67 | 0.77 | 4.57 | 0.72 | 4.48 | 0.77 | 4.49 | 0.73 | 4.50 | 0.72 | 4.50 | 0.70 | 4.46 | 0.68 | 4.50 | 0.69 | 4.46 | 0.64 | 4.52 | 0.69 | 4.52 | 0.69 | 4.58 | 0.64 | 0.231 | ||||
Brd | 4.60 | 0.58 | 4.69 | 0.66 | 4.57 | 0.62 | 4.54 | 0.66 | 4.46 | 0.59 | 4.55 | 0.62 | 4.57 | 0.60 | 4.48 | 0.60 | 4.50 | 0.57 | 4.48 | 0.58 | 4.52 | 0.65 | 4.55 | 0.67 | 4.58 | 0.65 | |||||
LDL-C (mmol/l) | |||||||||||||||||||||||||||||||
Glu | 2.79 | 0.64 | 2.84 | 0.67 | 2.76 | 0.65 | 2.69 | 0.66 | 2.68 | 0.64 | 2.72 | 0.63 | 2.72 | 0.62 | 2.71 | 0.61 | 2.72 | 0.62 | 2.71 | 0.61 | 2.75 | 0.64 | 2.73 | 0.63 | 2.76 | 0.59 | 0.476 | ||||
Brd | 2.81 | 0.57 | 2.86 | 0.61 | 2.78 | 0.60 | 2.76 | 0.62 | 2.70 | 0.57 | 2.76 | 0.59 | 2.76 | 0.56 | 2.71 | 0.55 | 2.72 | 0.55 | 2.73 | 0.56 | 2.76 | 0.60 | 2.77 | 0.59 | 2.80 | 0.59 | |||||
HDL-C (mmol/l) | |||||||||||||||||||||||||||||||
Glu | 1.50 | 0.33 | 1.53 | 0.36 | 1.49 | 0.34 | 1.46 | 0.34 | 1.46 | 0.34 | 1.47 | 0.34 | 1.48 | 0.34 | 1.47 | 0.33 | 1.49 | 0.33 | 1.48 | 0.31 | 1.49 | 0.33 | 1.49 | 0.34 | 1.51 | 0.37 | 0.408 | ||||
Brd | 1.47 | 0.31 | 1.52 | 0.35 | 1.48 | 0.32 | 1.47 | 0.31 | 1.44 | 0.31 | 1.46 | 0.34 | 1.47 | 0.34 | 1.45 | 0.32 | 1.45 | 0.31 | 1.45 | 0.32 | 1.46 | 0.31 | 1.47 | 0.33 | 1.48 | 0.32 | |||||
TAG (mmol/l) | |||||||||||||||||||||||||||||||
Glu | 0.91 | 0.27 | 0.92 | 0.28 | 0.94 | 0.29 | 0.96 | 0.32 | 0.95 | 0.33 | 0.87 | 0.32 | 0.82† | 0.31 | 0.80 | 0.28 | 0.83 | 0.29 | 0.87 | 0.29 | 0.92 | 0.29 | 0.98 | 0.29 | 1.01 | 0.29 | 0.017 | ||||
Brd | 0.88 | 0.27 | 0.89 | 0.27 | 0.92 | 0.24 | 0.94 | 0.27 | 0.93 | 0.30 | 0.93 | 0.33 | 0.91 | 0.31 | 0.89 | 0.32 | 0.89 | 0.30 | 0.90 | 0.30 | 0.93 | 0.32 | 0.95 | 0.33 | 0.98 | 0.33 | |||||
NEFA (mmol/l) | |||||||||||||||||||||||||||||||
Glu | 0.47 | 0.19 | 0.45 | 0.20 | 0.35 | 0.16 | 0.22† | 0.10 | 0.15* | 0.05 | 0.10† | 0.03 | 0.10 | 0.03 | 0.16 | 0.07 | 0.32 | 0.15 | 0.49* | 0.16 | 0.60* | 0.18 | 0.69* | 0.22 | 0.71 | 0.20 | 0.001 | ||||
Brd | 0.44 | 0.11 | 0.38 | 0.11 | 0.40 | 0.14 | 0.33 | 0.12 | 0.23 | 0.08 | 0.13 | 0.04 | 0.11 | 0.03 | 0.14 | 0.06 | 0.22 | 0.09 | 0.29 | 0.11 | 0.40 | 0.12 | 0.50 | 0.12 | 0.62 | 0.14 |
TC, total cholesterol; LDL-C, LDL-cholesterol; HDL-C, HDL-cholesterol.
Mean values were significantly different from those of the Brd challenge for each time point (P<001).
Mean values were significantly different from those of the Brd challenge for each time point (P<0.05).
The values represent the absolute concentrations for each outcome.