Table 2.
Correlation results in the 5 tumor-normal datasets.
| Bladder | Breast | Lung | HNSCC | Osteosarcoma | |
|---|---|---|---|---|---|
| (A) PEARSON'S CORRELATION RESULTS | |||||
| Absolute estimate | 0.053 | 0.023 | −0.022 | 0.013 | 0.029 |
| Absolute mean P-value | 1.98 × 10−12 | 0.061 | 1.72 × 10−35 | 0.033 | 6.2 × 10−4 |
| FDR Q-value | 4.95 × 10−12 | 0.061 | 8.65 × 10−35 | 0.041 | 1.00 × 10−3 |
| 1000 random permutations on datasets of equal size | |||||
| Positive values are higher in normal samples | |||||
| Estimate | −0.046 | 0.053 | 0.044 | 0.024 | 0.06 |
| P-value | 6.35 × 10−10 | 2.20 × 10−16 | 2.20 × 10−16 | 1.09 × 10−9 | 7.59 × 10−15 |
| FDR Q-value | 7.93 × 10−10 | 5.50 × 10−16 | 5.50 × 10−16 | 1.09 × 10−9 | 1.26 × 10−14 |
| (B) SPEARMAN'S CORRELATION RESULTS | |||||
| Absolute Estimate | 0.023 | −0.006 | −0.018 | 0.009 | 0.033 |
| Absolute Mean P-value | 0.0082 | 0.21 | 1.43 × 10−26 | 0.061 | 8.04 × 10−7 |
| FDR Q-value | 0.014 | 0.21 | 7.15 × 10−26 | 0.077 | 2.01 × 10−6 |
| 1000 random permutations on datasets of equal size | |||||
| Positive values are higher in normal samples | |||||
| Estimate | −0.036 | 0.049 | 0.038 | 0.018 | 0.055 |
| P-value | 2.37 × 10−7 | 2.20 × 10−16 | 2.20 × 10−16 | 7.51 × 10−7 | 8.69 × 10−13 |
| FDR Q-value | 2.96 × 10−7 | 5.50 × 10−16 | 5.50 × 10−16 | 7.51 × 10−7 | 1.44 × 10−12 |
(A) Person's correlations for absolute correlation (upper table) and signed correlation (lower table) differences. Reported estimates are the mean of the 95% CI obtained after calculating correlations in 1000 random subsets of the same population size. (B) Spearman's correlations for absolute (upper table) and signed (lower table) correlation differences. Reported estimates are the mean of the 95% CI.