TABLE 3.

Depletion half-lives of steroid hormones when incubated with HepaRG cells or SCHH

Hormone		HepaRG Cell		SCHH
		Concentration	Half-Life	Concentration	Half-Life
		nM	Hours	nM	Hours
Estradiol	1×	51	NQ	319	2.0 ± 0.5*
	10×	510	3.3 ± 0.7	3187	1.6 ± 0.4*
Progesterone	1×	395	7.5 ± 1.0	705	1.4 ± 0.4*
	10×	3950	9.2 ± 0.7	19,100	1.6 ± 1.0*
Cortisol	Unbound	16.3	13.0 ± 2.4*	48.8	NQ
	1×	798	ND	798	ND
	10×	7980	ND	7980	ND

ND, no depletion; NQ, not quantified; data expressed as mean ± S.D.; *, n = 3.