Skip to main content
. Author manuscript; available in PMC: 2015 May 13.
Published in final edited form as: Toxicol Appl Pharmacol. 2012 Apr 19;262(1):11–21. doi: 10.1016/j.taap.2012.04.014

Figure 4.

Figure 4

Carcinogenic metals alone increased the expression of β-catenin and phospho-GSK3β in the colon tissue. (A) The mice received As(III), Cr(VI), or As(III)+Cr(VI) in drinking water alone for 20 weeks. The expression of β-catenin and phospho-GSK3β in indicated treatment were determined with immunoblotting. The expression of actin served as an internal control. (B) The relative amounts of β-catenin and phospho-GSK3β was quantified microdensitometrically and normalized to the expression of actin. Each data point was the mean ± SEM of three independent experiments. *p < 0.05, statistically significant difference from control group.