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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Nat Med. 2015 Feb 23;21(3):239–247. doi: 10.1038/nm.3800

Figure 6.

Figure 6

Ltb4r1 inhibitor improves hepatic steatosis. (a) HE staining of liver from HFD or ob/ob mice treated with vehicle or Ltb4r1 inhibitor. The scale bar indicates 50 μm. (b) Relative mRNA levels of lipogenesis/gluconeogenesis genes in liver of HFD mice treated with vehicle or Ltb4r1 inhibitor. (c) Effect of LTB4 on DAG content in hepatocytes. (d) Effect of LTB4 on ceramides content in hepatocytes. Data were analyzed by two-way ANOVA followed by Bonferroni post tests. Values are expressed as mean ± s.e.m. n=6 in a-d. * P<0.05, ** P<0.01 for vehicle versus treatment, or KO versus WT.