The impact of taxol on the morphology of parkin-deficient neurons. (A–H) Representative morphology of P001 (A, B) or P002 (C, D) TH+ neurons treated with vehicle (A, C) or taxol (1 nM for 14 days) (B, D) and quantification of their total neurite length (E), number of terminals (F), number of branch points (G) and Sholl analysis (H). (I–P) Representative morphology of P001 (I, J) or P002 (K, L) TH− neurons treated with vehicle (I, K) or taxol (1 nM for 14 days) (J, L) and quantification of their total neurite length (M), number of terminals (N), number of branch points (O) and Sholl analysis (P). *, p < 0.001, vs. vehicle-treated P001 or P002, n = 52 TH+ neurons and n = 54 TH− neurons for each condition of P001 or P002 neurons, all from three independent experiments.