Table 1. Total distance traveled during 1-h test period in mice treated with PACAP (1.0 μg/3.0 μL; ICV) or vehicle before and following morphine (5 mg/kg) administration.

Treatment/animal ID	Vehicle	PACAP
Before morphine
1	710	114
2	460	150
3	642	0
4	488	201
5	336	183
6	513	84
Mean (±SEM)	532±58	122±30*
After morphine
1	3,742	2,218
2	4,520	3,023
3	7,010	1.5
4	5,549	1,982
5	2,648	2,331
6	3,585	6.2
Mean (±SEM)	5,369± 1,067	1,577±518*

^*p<0.05, unpaired Student's t test

Data represent mean (±SEM) of six mice per treatment