Table 2.
The amount of time that mutant mice (PACAP−/−) and their wild-type littermates/controls (PACAP+/+) spent in the morphine-paired chamber (MOR-paired) and saline-paired chamber (SAL-paired) prior to (preconditioning) and following single or repeated conditioning with morphine
Genotype/test day | SAL-paired | MOR-paired |
---|---|---|
PACAP (+/+) | ||
Preconditioning | 302±22 | 311 ±32 |
Single conditioning | 193 ±16 | 396±32 |
Repeated conditioning | 202±13 | 366±25 |
PACAP (−/−) | ||
Preconditioning | 301 ± 16 | 302±23 |
Single conditioning | 246±24 | 289±27 |
Repeated conditioning | 187 ±15 | 373 ±24 |
Data represent mean (±SEM) of seven mice per genotype