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. Author manuscript; available in PMC: 2015 May 13.
Published in final edited form as: J Neurosci Res. 2009 Nov 15;87(15):3511–3519. doi: 10.1002/jnr.21981

Table II.

Increased Lymphocytic Infiltration of the CNS of Treg-Depleted Mice

Treatment Cell Numbers in the CNS × 103
CD4+ T Cells CD8+ T Cells B220+ B Cells
Rat IgG 13 3 9
PC61 49 14 24

C57BL/6 mice that had received three i.p. injections of either rat IgG orPC61 were immunized by standard protocol with mouse MOG, then sacrificed on day 20. Mononuclear cells were isolated from the CNS and stained with anti-CD4, anti-CD8 and anti-B220 antibodies as described in Methods. Cell frequencies were used to calculate the absolute cell numbers of each population out of the total number of isolated cells.