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. 2015 May 3;15:72. doi: 10.1186/s12883-015-0324-2

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© Nicholas et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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South Asian MS patients show a broader myelin T cell response. Compared to Caucasians with MS (A and B, column 1) there were increased numbers of recognized T cell epitopes in UK born South Asians (A and B, column 2) for both MBP (A, *p = 0.009) and MOG (B, **p = 0.017). In non-UK born South Asians, there was an increase in the number of recognized T cell epitopes in those with a disease onset greater than or equal to 30 years (A and B, column 4) compared to those with a disease onset under the age of 30 years (A and B, column 3). This was significant for both MBP (A, **p = 0.036) and MOG (B, ****p = 0.015).