Table 1.
Gene | Species | IRF family | of which IRF3 | NF-κB family | of which REL |
---|---|---|---|---|---|
IRF1 | Human (var*) | 1 | 0 | 37 | 13 |
Mouse (var) | 0 | 0 | 23 | 8 | |
Chimpanzee | 1 | 0 | 37 | 13 | |
Cattle | 2 | 0 | 40 | 14 | |
IRF2 | Human | 7 | 2 | 12 | 6 |
Mouse (var) | 8 | 2 | 24 | 8 | |
Chimpanzee | 4 | 1 | 10 | 7 | |
Cattle | 8 | 2 | 21 | 7 | |
IRF3 | Human (var) | 1 | 1 | 5 | 4 |
Mouse (var) | 2 | 1 | 17 | 9 | |
Chimpanzee | 2 | 1 | 5 | 4 | |
Cattle | 2 | 1 | 12 | 5 | |
NFKB1 | Human | 6 | 2 | 21 | 6 |
Mouse (var) | 1 | 0 | 3 | 2 | |
Chimpanzee | 5 | 2 | 19 | 5 | |
Cattle | 5 | 0 | 2 | 2 | |
NFKB2 | Human (var) | 0 | 0 | 24 | 8 |
Mouse (var) | 0 | 0 | 24 | 8 | |
Chimpanzee | 0 | 0 | 25 | 8 | |
Cattle | 0 | 0 | 27 | 9 | |
RELA | Human | 1 | 0 | 18 | 6 |
Mouse | 2 | 1 | 14 | 6 | |
Chimpanzee | 1 | 0 | 6 | 2 | |
Cattle | 0 | 0 | 8 | 4 | |
REL | Human | 1 | 0 | 28 | 5 |
Mouse | 0 | 0 | 28 | 7 | |
Chimpanzee | 1 | 0 | 21 | 3 | |
Cattle | 7 | 0 | 4 | 1 |
Summary of the counts of TFBS corresponding to the members of IRF and NF-κB families of transcription factors found in the promoters of presented genes in four species: human, mouse chimpanzee and cattle. Motifs overlap; numbers in bold correspond to promoters containing 2 or more IRF3 motifs. Detailed results are presented in Additional file 1. *var – other variants of the promoter exist.