Table 2.
Survival analysis of the association of admixture with diabetes risk
| Groupa | Admixtureb | Model | HR | 95% CI | p value |
|---|---|---|---|---|---|
| All | AFR | Age | 1.82 | 1.63, 2.04 | 3.2×10−25 |
| AFR | Age, SES | 1.64 | 1.46, 1.83 | 1.7×10−17 | |
| AFR | Age, SES, BMI | 1.33 | 1.19, 1.50 | 9.8×10−7 | |
| AFR | Age, SES, WHR | 1.58 | 1.41, 1.77 | 2.0×10−15 | |
| EUR | Age | 0.39 | 0.33, 0.45 | 1.3×10−32 | |
| EUR | Age, SES | 0.46 | 0.39, 0.54 | 8.9×10−22 | |
| EUR | Age, SES, BMI | 0.59 | 0.50, 0.69 | 9.0×10−11 | |
| EUR | Age, SES, WHR | 0.50 | 0.43, 0.59 | 3.7×10−17 | |
| AMI | Age | 0.69 | 0.55, 0.88 | 1.6×10−3 | |
| AMI | Age, SES | 0.70 | 0.55, 0.88 | 2.3×10−3 | |
| AMI | Age, SES, BMI | 0.97 | 0.77, 1.23 | 8.2×10−1 | |
| AMI | Age, SES, WHR | 0.64 | 0.50, 0.80 | 1.3×10−4 | |
| AFA | AFR | Age | 3.08 | 2.24, 4.24 | 4.8×10−12 |
| AFR | Age, SES | 2.36 | 1.71, 3.27 | 2.3×10−7 | |
| AFR | Age, SES, BMI | 2.02 | 1.46, 2.80 | 2.2×10−5 | |
| AFR | Age, SES, WHR | 2.23 | 1.61, 3.09 | 1.5×10−6 | |
| HA | AFR | Age | 1.11 | 0.64, 1.92 | 7.2×10−1 |
| AFR | Age, SES | 0.91 | 0.53, 1.59 | 7.5×10−1 | |
| AFR | Age, SES, BMI | 0.84 | 0.48, 1.48 | 5.6×10−1 | |
| AFR | Age, SES, WHR | 0.98 | 0.57, 1.68 | 9.3×10−1 | |
| EUR | Age | 0.40 | 0.28, 0.57 | 5.1×10−7 | |
| EUR | Age, SES | 0.54 | 0.37, 0.77 | 8.4×10−4 | |
| EUR | Age, SES, BMI | 0.54 | 0.37, 0.78 | 1.0×10−3 | |
| EUR | Age, SES, WHR | 0.71 | 0.49, 1.04 | 7.7×10−2 | |
| AMI | Age | 2.50 | 1.74, 3.60 | 8.8×10−7 | |
| AMI | Age, SES | 1.97 | 1.36, 2.84 | 3.1×10−4 | |
| AMI | Age, SES, BMI | 2.03 | 1.40, 2.95 | 1.9×10−4 | |
| AMI | Age, SES, WHR | 1.42 | 0.97, 2.06 | 6.7×10−2 |
SES, BMI and WHR were divided by their SDs
a
Groups are defined as noted in the footnote to Table 1
b
The AFR, AMI or EUR admixture was used as the covariate of interest in separate models, adjusting for the variables listed in each model: age (entry age), SES and BMI or WHR