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. 2015 May 13;9(5):e0003763. doi: 10.1371/journal.pntd.0003763

Table 1. Baseline and intervening time point demographic and clinical characteristics of (A) 585 Ethiopian participants and (B) 577 Tanzanian participants included in the analysis of progression of conjunctival scarring.

Characteristic Progressors Non-Progressors P-value
A) ETHIOPIA N = 135 N = 450
Gender (female) 93 (68.9%) 280 (62.2%) 0.16
Age at baseline, mean (SD) 49.4 (13.4) 50.6 (14.5) 0.42
BMI at baseline, mean (SD) 20.1 (2.4) 20.0 (2.3) 0.73
Scarring severity at baseline <0.0001
1a 0 - 1 (0.2%)
1b 6 (4.4%) 4 (0.9%)
1c 20 (14.8%) 21 (4.7%)
2 107 (79.3%) 342 (76.0%)
3 2 (1.5%) 82 (18.2%)
Clinically inflamed (P2/P3)
Baseline 71 / 135 (52.6%) 136 / 450 (30.2%) <0.0001
6-months 26 / 95 (27.4%) 50 / 341 (14.7%) 0.0039
12-months 58 / 130 (44.6%) 84 / 430 (19.4%) <0.0001
18-months 29 / 131 (22.1%) 60 / 436 (13.8%) 0.021
Clinically inflamed, 1+ episode 97 (71.9%) 192 (42.7%) <0.0001
Proportion of examinations with inflammation (%) <0.0001
0% 38 (28.1%) 258 (57.3%)
25% 28 (20.7%) 77 (17.1%)
33% 11 (8.1%) 25 (5.6%)
50% 19 (14.1%) 32 (7.1%)
66% 9 (6.7%) 16 (3.6%)
75% 11 (8.1%) 18 (4.0%)
100% 19 (14.1%) 24 (5.3%)
B) TANZANIA N = 173 N = 404
Gender (female) 115 (66.5%) 247 (61.1%) 0.23
Age at baseline, mean (SD) 50.9 (17.7) 43.8 (16.9) <0.0001
BMI at baseline, mean (SD) 21.6 (3.1) 21.8 (2.9) 0.47
Scarring severity at baseline <0.0001
1a 45 (26.0%) 170 (42.1%)
1b 63 (36.4%) 170 (42.1%)
1c 45 (26.0%) 47 (11.6%)
2 14 (8.1%) 12 (3.0%)
3 6 (3.5%) 5 (1.2%)
Clinically inflamed (P2/P3)
Baseline 46 / 173 (26.6%) 55 / 404 (13.6%) 0.0002
6-months 21 / 152 (13.8%) 15 / 357 (14.7%) 0.0001
12-months 13 / 143 (9.1%) 16 / 335 (4.8%) 0.070
18-months 6 / 135 (4.4%) 3 / 325 (1.0%) 0.013
Clinically inflamed, 1+ episode 53 / 173 (30.6%) 69 / 404 (17.1%) 0.0003
Proportion of examinations with inflammation (%) 0.0011
0% 120 (69.4%) 335 (82.9%)
25% 19 (11.0%) 37 (9.2%)
33% 8 (4.6%) 13 (3.2%)
50% 8 (4.6%) 9 (2.2%)
66% 3 (1.7%) 2 (0.5%)
75% 5 (2.9%) 2 (0.5%)
100% 10 (5.8%) 6 (1.5%)