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Treatment efficacy
| Paclitaxel/carboplatin/sorafenib (N = 43) | Paclitaxel/carboplatin (N = 42) | |
|---|---|---|
| Response | ||
| Complete | 16 (37%) | 18 (43%) |
| Partial | 13 (30%) | 13 (31%) |
| Stable | 8 (19%) | 9 (21%) |
| Progression | 0 | 1 (2%) |
| Unevaluable | 6 (14%) | 1 (2%) |
| Overall response rate | 29/43 (67%) | 31/42 (74%) |
| Progression-free survival | ||
| Median, months | 15.4 | 16.3; P = 0.38 |
| 2-years (%) | 40% | 40% |
| Overall survival | ||
| Median | 36.5 | NA; P = 0.12 |
| 2-year | 76% | 81% |
| 3-year | 56% | 61% |
