Fig 8. Seizure lengths according to inter-population coupling (left) and background noise (right).

Simulations were performed to reproduce 15 minutes of activity for each parameter setting, resulting in 10 to 30 seizures per simulations. Mean, minimum and maximum seizure lengths were calculated from these generated time series by isolating the fast firing neurons’ activity and counting the time spent in up-state (threshold at -40 mV). Up-states of less than 5s were not considered as seizure and down-states of less than 3s between consecutive seizures were considered as being part of the same seizure. Noise is inserted in both excitatory and inhibitory neurons. Parameters: C_E = 0.8, x₀ = 3.0; W_max = 0.2 (left plot); G_s ^i,j = 0.1 (right plot); G_s ^i,i = 0.1; r = 0.000004.