Table 4.
First-order partial correlation for BMI or waist circumference (Wc) with atherothrombotic risk factors
CVD risk factors | Partial correlation for BMI with a risk factor (independent of WC)
|
Partial correlation for WC with a risk factor (independent of BMI)
|
||
---|---|---|---|---|
Coefficient | P value | Coefficient | P value | |
HDL-cholesterol | 0.135 | <0.001 | −0.191 | <0.001 |
Log of triglycerides | −0.020 | 0.346 | 0.072 | <0.001 |
Systolic BP | 0.066 | 0.002 | −0.050 | 0.018 |
Diastolic BP | 0.042 | 0.044 | −0.035 | 0.096 |
Log of AC ratio | 0.035 | 0.106 | 0.006 | 0.776 |
HbA1c | 0.02 | 0.342 | −0.038 | 0.067 |
Log of insulin | 0.071 | <0.001 | 0.104 | <0.001 |
Log of PAI-1 activity | 0.08 | <0.001 | 0.061 | 0.005 |
Log of PAI-1 antigen | 0.080 | <0.001 | 0.034 | 0.242 |
Log of CRP | 0.179 | <0.001 | −0.010 | 0.621 |
Fibrinogen | 0.093 | <0.001 | −0.021 | 0.315 |
Log of D-dimer | 0.033 | 0.121 | −0.014 | 0.509 |
To see if waist circumference, independent of BMI, or BMI independent of waist circumference, has the stronger association with a risk factor, the partial correlation coefficient should have significant absolute value and persist in the original direction consistent with common sense.
BP, blood pressure; AC ratio, urinary albumin/creatinine ratio; PAI-1, plasminogen-activator inhibitor 1; CRP. C-reactive protein.