Skip to main content
. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Bioorg Med Chem Lett. 2015 Apr 23;25(11):2280–2284. doi: 10.1016/j.bmcl.2015.04.041

Table 1.

Inhibition of GROα-mediated intracellular calcium release in isolated human PMNs.

Cpd R IC50 (nM) a Cpd R IC50 (nM)
5 graphic file with name nihms683973t1.jpg 38 ± 3 8 graphic file with name nihms683973t2.jpg 1220 ± 750
9 graphic file with name nihms683973t3.jpg 90 ± 15 10 graphic file with name nihms683973t4.jpg 689 ± 239
11 graphic file with name nihms683973t5.jpg 387 ± 125 12 graphic file with name nihms683973t6.jpg >10,000
13 graphic file with name nihms683973t7.jpg >10,000 14 graphic file with name nihms683973t8.jpg 80 ± 8
15 graphic file with name nihms683973t9.jpg 52 ± 6 6 graphic file with name nihms683973t10.jpg 22 ± 3
a

Experiments performed in triplicate, reported as mean ± SE.