Table 4.
Significant correlations (Pearson’s R) and P values between clinical variables and HRQOL measures in morphea.
| Skindex-Symptoms | Skindex-Emotions | Skindex-Functioning | Skindex-Morphea-Specific | DLQI | SF-36 PCS | SF-36 MCS | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| R | P | R | P | R | P | R | P | R | P | R | P | |||
| SCQ | .4430 | .0001* | .2203 | .0689 | .4655 | <.0001* | .3552 | .0027* | .4504 | .0001* | .5066 | <.0001* | .3534 | (.0029)* |
| Pain | .7441 | <.0001* | .1966 | .1055 | .4555 | <.0001* | .4813 | <.0001* | .5289 | <.0001* | .4755 | <.0001* | .2402 | (.0468) |
| Itch | .6439 | <.0001* | .1263 | .3012 | .2188 | .0709 | .3818 | .0012* | .2308 | .0583 | .2225 | .0662 | .2053 | (.0907) |
| Functional Limitation | .1793 | .1292 | .0642 | .5895 | .1101 | .3537 | .3599 | .0018* | .1750 | .1414 | .3754 | .0011* | .0376 | (.7519) |
| LoSSI | .5570 | <.0001* | .0885 | .4866 | .2665 | .0333 | .3376 | .0064* | .2750 | .0292 | .4163 | .0006* | .1905 | (.1316) |
| PGA-A | .5930 | <.0001* | .2222 | .0729 | .3887 | .0013* | .3738 | .0020* | .3948 | .0011* | .3708 | .0022* | .2860 | (.0199) |
| LoSDI | .1282 | .3127 | .0937 | .4615 | .0872 | .4935 | .1907 | .1312 | .1337 | .2960 | .3949 | .0012* | .0773 | (.5436) |
| PGA-D | .1171 | .3529 | .1000 | .4280 | .2099 | .0933 | .1632 | .1941 | .1782 | .1588 | .2812 | .0233 | .0602 | (.6341) |
| MRSS | .3191 | .0085* | .0288 | .8189 | .2228 | .0700 | .3050 | .0121* | .1959 | .1149 | .4548 | .0001* | .0782 | (.5294) |
Statistical Significant finding (r ≥.30, P<.01) to minimize associations made by chance alone.
A. Clinical variables significantly correlated with impaired HRQOL in one or more Skindex-29+3 or SF-36 subscales as designated by Pearson correlation coefficients ≥.30 and P <.05 are depicted. C. Pearson correlation coefficients between disease severity as measured by the LoSCAT and HRQOL measures are shown.
DLQI, Dermatology Life Quality Index; LoSDI, Localized Scleroderma Skin Damage Index; LoSSI, Localized Scleroderma Skin Severity Index; MCS, mental component summary; MRSS, modified Rodnan skin score; PCS, physical component summary; PGA-A, Physician Global Assessment-Activity; PGA-D, Physician Global Assessment-Damage; SCQ, Self-Administered Comorbidity Questionnaire.